{"title":"Sleep Support","description":null,"products":[{"product_id":"pure-sleep-60ct","title":"Pure Sleep 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Helps your patients fall asleep, stay asleep, and wake up refreshed without morning grogginess\u003cbr\u003e* Improves sleep quality, efficiency and duration with continued use\u003cbr\u003e* Helps relieve occasional stress and anxiety\u003cbr\u003e* Supports a healthy cortisol response\u003cbr\u003e* Melatonin free\u003cbr\u003e* Clinically studied ashwagandha (KSM-66)\u003cbr\u003e* Clinically studied saffron (affron®)\u003cbr\u003e* Clinically studied valerian root (Sleeproot)\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 2 capsules, 30-60 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* For patients seeking support for sleep onset and\/or duration\u003cbr\u003e* For patients requesting a melatonin-free product\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003ePure Sleep combines three clinically studied botanical extracts to help patients fall asleep, stay asleep and experience the restorative, restful sleep they need without morning grogginess. KSM-66 ® ashwagandha (*Withania somnifera* ) root extract is a calming adaptogen that helps relieve occasional stress and anxiety and supports a healthy cortisol response.1, 2 Results from several randomized, placebo-controlled trials indicate that KSM-66 ® supports sleep onset, helping individuals fall asleep faster, while enhancing sleep quality and efficiency when taken continuously over several weeks.2-4 In a randomized, double blind clinical trial involving 80 adults, ashwagandha supplementation (KSM-66 ®, 300 mg twice daily) for 8 weeks led to a significant mean reduction in sleep onset latency (the time it takes to fall asleep after going to bed), sleep quality, and total sleep time.3 A 12- week randomized, double blind clinical trial demonstrated that ashwagandha (KSM-66 ®, 300 mg twice daily) improved subjective sleep parameters and mental alertness on rising, in healthy elderly subjects.4 Results from multiple clinical trials demonstrate that saffron extract (affron ®) promotes multiple aspects of restful sleep, supporting sleep onset and duration with continued use.5-7 In a randomized, double blind clinical trial involving 66 adults, saffron (affron ®, 15.5 mg per day) for 6 weeks led to significant improvements in ease of getting to sleep, sleep quality, sleep duration, and global Pittsburgh Sleep Quality Index (PSQI) scores.5 In a randomized double-blind, placebo controlled trial involving 63 healthy adults aged 18-70 with self-reported sleep concerns, saffron (affron ®, 14 mg twice daily) for 28 days led to greater improvements in Restorative Sleep Questionnaire (RSQ) total scores and the Pittsburgh Sleep Diary (PSD) sleep quality ratings compared to placebo.6 This formula also provides Sleeproot, a valerian root extract standardized to a higher potency (2% total valerenic acids) than typical extracts, that promotes sleep quality, efficiency and duration. In a randomized, double blind clinical trial involving 72 adults, Sleeproot (200 mg\/day) for 8 weeks improved overall sleep quality, reduced sleep latency, enhanced sleep efficiency, and prolonged total sleep time. Sleeproot resulted in significant improvements in mean total PSQI sleep scores and reduced sleep latency, assessed by wrist actigraphy, compared to placebo.8\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Salve J, et al. *Cureus* 2019 Dec 25;11(12):e6466.\u003cbr\u003e2. Langade D, et al. *Cureus* 2019; 11(9): e5797.\u003cbr\u003e3. Langade D, et al. *J Ethnopharmacol*. 2021; 264: 113276.\u003cbr\u003e4. Kelgane SB, et al. *Cureus* 2020; 12(2): e7083.\u003cbr\u003e5. Pachikian BD, et al. *Nutrients* 2021 Apr 27;13(5):1473.\u003cbr\u003e6. Lopresti AL, et al. *J Clin Sleep Med*. 2020 Jun 15;16(6):937-947.\u003cbr\u003e7. Lopresti AL, et al. *Sleep Med*. 2021 Oct;86:7-18.\u003cbr\u003e8. Shekhar CH, et al. Adv Ther. 2024 Jan;41(1):246-261.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eNot to be taken if you are pregnant or lactating. Consult your healthcare practitioner before use if on any medication or have any health condition. Discontinue use and seek medical advice if adverse reaction occur. Product may impair ability to drive a motor vehicle or operate machinery.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Ashwagandha extract is derived from *Withania somnifera* root\u003cbr\u003e* Valerian extract is derived from *Valeriana officinalis* root\u003cbr\u003e* Theanine is derived from fermentation\u003cbr\u003e* Saffron is derived from *Crocus sativus* stigma extract\u003cbr\u003e* Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose\u003cbr\u003e* Tri-magnesium citrate is derived from elemental ore and non-GMO glucose fermentation from non-GMO maize, molasses, and sugar beet or sugar cane\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275299967172,"sku":null,"price":52.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/psl6_rgb.avif?v=1781887673"},{"product_id":"best-rest-formula-60ct","title":"Best-Rest Formula 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Promotes the onset of sleep as well as sleep quality\u003cbr\u003e* Supports natural relaxation of the nervous system\u003cbr\u003e* Made with flower extracts and other natural ingredients\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 2 capsules, 30-60 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Restful sleep and relaxation support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eBest Rest Formula provides support for occasional sleeplessness. It contains the time-tested support of valerian, passionflower, chamomile, lemon balm and hops, which act to calm and relax the central nervous system. Double-blind trials involving valerian, valerian\/lemon balm combinations and valerian\/hops combinations have indicated the potential to support the onset of sleep as well as healthy sleep quality.1-3 Melatonin also facilitates the onset of sleep and sleep efficiency.4 GABA and L-theanine are included for their ability to promote alpha wave production in the brain, an indication of relaxation.5, 6\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Kennedy DO, et. al. *Phytother Res*. 2006 Feb;20(2):96-102.\u003cbr\u003e2. Ngan A, et. al. *Phytother Res* 2011 Aug;25(8):1153-9.\u003cbr\u003e3. Zick SM, et. al. *BMC Complement Altern Med*. 2011 Sep 22;11:78.\u003cbr\u003e4. Eckerberg B, et. al. *Chronobiol Int* 2012 Nov;29(9):1239-48.\u003cbr\u003e5. Yoto A, et. al. *Amino Acids* 2012 Sep;43(3):1331-7.\u003cbr\u003e6. Kimura K, et. al. *Biol Psychol* 2007 Jan;74(1):39-45.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.\u003c\/p\u003e\n\u003cp\u003eDo not drive or operate machinery when taking melatonin.\u003c\/p\u003e\n\u003cp\u003eThis product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Pyridoxal-5-phosphate, melatonin and GABA (gamma-aminobutyric acid) are synthetic.\u003cbr\u003e* Theanine is derived from fermentation.\u003cbr\u003e* Deodorized valerian extract is derived from *Valeriana officinalis* root and standardized to contain 0.8% valernic acids.\u003cbr\u003e* Lemon balm extract is derived from *Melissa officinalis* leaf and standardized to contain 5% rosemarinic acid.\u003cbr\u003e* Hops is derived from *Humulus lupulus L*. aerial parts and standardized to contain 2.9% flavonoids.\u003cbr\u003e* Passionflower extract is derived from *Passiflora incarnata L.* aerial parts and standardized to contain 3.5% vitexin.\u003cbr\u003e* Chamomile extract is derived from *Matricaria recutita* flowers.\u003cbr\u003e* Maltodextrin is derived from potato.\u003cbr\u003e* Gum arabic is derived from acacia tree.\u003cbr\u003e* Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil.\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275321069764,"sku":null,"price":37.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/631557883b6d7944f249fbbf06e1c20315c30ca03b0488b9105a92b67eaf7125.avif?v=1781957762"},{"product_id":"best-rest-formula-120ct","title":"Best-Rest Formula 120ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Promotes the onset of sleep as well as sleep quality\u003cbr\u003e* Supports natural relaxation of the nervous system\u003cbr\u003e* Made with flower extracts and other natural ingredients\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 2 capsules, 30-60 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Restful sleep and relaxation support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eBest Rest Formula provides support for occasional sleeplessness. It contains the time-tested support of valerian, passionflower, chamomile, lemon balm and hops, which act to calm and relax the central nervous system. Double-blind trials involving valerian, valerian\/lemon balm combinations and valerian\/hops combinations have indicated the potential to support the onset of sleep as well as healthy sleep quality.1-3 Melatonin also facilitates the onset of sleep and sleep efficiency.4 GABA and L-theanine are included for their ability to promote alpha wave production in the brain, an indication of relaxation.5, 6\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Kennedy DO, et. al. *Phytother Res*. 2006 Feb;20(2):96-102.\u003cbr\u003e2. Ngan A, et. al. *Phytother Res* 2011 Aug;25(8):1153-9.\u003cbr\u003e3. Zick SM, et. al. *BMC Complement Altern Med*. 2011 Sep 22;11:78.\u003cbr\u003e4. Eckerberg B, et. al. *Chronobiol Int* 2012 Nov;29(9):1239-48.\u003cbr\u003e5. Yoto A, et. al. *Amino Acids* 2012 Sep;43(3):1331-7.\u003cbr\u003e6. Kimura K, et. al. *Biol Psychol* 2007 Jan;74(1):39-45.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.\u003c\/p\u003e\n\u003cp\u003eDo not drive or operate machinery when taking melatonin.\u003c\/p\u003e\n\u003cp\u003eThis product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Pyridoxal-5-phosphate, melatonin and GABA (gamma-aminobutyric acid) are synthetic.\u003cbr\u003e* Theanine is derived from fermentation.\u003cbr\u003e* Deodorized valerian extract is derived from *Valeriana officinalis* root and standardized to contain 0.8% valernic acids.\u003cbr\u003e* Lemon balm extract is derived from *Melissa officinalis* leaf and standardized to contain 5% rosemarinic acid.\u003cbr\u003e* Hops is derived from *Humulus lupulus L*. aerial parts and standardized to contain 2.9% flavonoids.\u003cbr\u003e* Passionflower extract is derived from *Passiflora incarnata L.* aerial parts and standardized to contain 3.5% vitexin.\u003cbr\u003e* Chamomile extract is derived from *Matricaria recutita* flowers.\u003cbr\u003e* Maltodextrin is derived from potato.\u003cbr\u003e* Gum arabic is derived from acacia tree.\u003cbr\u003e* Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil.\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275321102532,"sku":null,"price":66.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/631557883b6d7944f249fbbf06e1c20315c30ca03b0488b9105a92b67eaf7125_1.avif?v=1781957849"},{"product_id":"glycine-180ct","title":"Glycine 180ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003ePromotes healthy kidney and liver function\u003cbr\u003eMay support nervous system health\u003cbr\u003eSupports detoxification\u003cbr\u003eMade with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 3 capsules, 1-2 times daily, between meals.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eAges 18 and up\u003cbr\u003eSleep and detoxification support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eGlycine is the simplest amino acid; its side chain consists of just a single hydrogen atom. Supplementation with glycine has been shown to support healthy kidney and liver function as well as nervous system health. Animal studies and a small human study indicate that glycine has the potential to support memory and mental function.1 In another human trial, glycine, acting as an inhibitory amino acid, had neuroprotective effects.2 Animal studies suggest that glycine plays a protective role for the kidneys and liver particularly by supporting detoxification of certain chemicals.3\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Bannai M, et al. *Front Neurol*. 2012 Apr 18;3:61.\u003cbr\u003e2. File SE, et al. *J Clin Psychopharmacol*. 1999 Dec;19(6):506-12.\u003cbr\u003e3. Yang S, et al. *Critical Care Medicine*. 2001. 29(6); 1201-1206.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003eGlycine is synthetically produced\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275335618756,"sku":null,"price":35.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/b9acd9290e26c5fb311c49e5407b3a9a75d112ced1abae652ccaddde894a9f1b.avif?v=1781970569"},{"product_id":"melatonin-3-mg-30ct","title":"Melatonin 3 Mg 30ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003eSupports the body's natural sleep cycle\u003cbr\u003eHelps promote restful sleep\u003cbr\u003eSupports antioxidant defenses\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003e1 capsule daily, 1\/2 to 1 hour before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eIndividuals seeking to support the body's natural sleep cycle\u003cbr\u003eIndividuals experiencing occasional sleeplessness\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland that helps to regulate the body's sleep-wake cycle. It is involved in numerous aspects of cellular and physiological function, including the regulation of the sleep-wake cycle, immune function, and antioxidant defense systems. Melatonin helps to initiate and maintain sleep by signaling the body's readiness for sleep. It also helps to regulate circadian rhythms, which are the natural 24-hour cycles that control various bodily functions. Melatonin has been shown to support antioxidant defenses by scavenging free radicals and enhancing the activity of antioxidant enzymes. It also plays a role in immune function by modulating the activity of immune cells.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340763332,"sku":null,"price":11.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/4c1a03e2f6a50eb5dfb40a2081f114957b1828d965a5f47e0650066ef0d2f2f1_1.avif?v=1782128166"},{"product_id":"melatonin-3-mg-60ct","title":"Melatonin 3 Mg 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003eSupports the body's natural sleep cycle\u003cbr\u003eHelps promote restful sleep\u003cbr\u003eSupports antioxidant defenses\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003e1 capsule daily, 1\/2 to 1 hour before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eIndividuals seeking to support the body's natural sleep cycle\u003cbr\u003eIndividuals experiencing occasional sleeplessness\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland that helps to regulate the body's sleep-wake cycle. It is involved in numerous aspects of cellular and physiological function, including the regulation of the sleep-wake cycle, immune function, and antioxidant defense systems. Melatonin helps to initiate and maintain sleep by signaling the body's readiness for sleep. It also helps to regulate circadian rhythms, which are the natural 24-hour cycles that control various bodily functions. Melatonin has been shown to support antioxidant defenses by scavenging free radicals and enhancing the activity of antioxidant enzymes. It also plays a role in immune function by modulating the activity of immune cells.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340796100,"sku":null,"price":15.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/4c1a03e2f6a50eb5dfb40a2081f114957b1828d965a5f47e0650066ef0d2f2f1_4.avif?v=1782128432"},{"product_id":"melatonin-3-mg-180ct","title":"Melatonin 3 Mg 180ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003eSupports the body's natural sleep cycle\u003cbr\u003eHelps promote restful sleep\u003cbr\u003eSupports antioxidant defenses\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003e1 capsule daily, 1\/2 to 1 hour before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eIndividuals seeking to support the body's natural sleep cycle\u003cbr\u003eIndividuals experiencing occasional sleeplessness\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland that helps to regulate the body's sleep-wake cycle. It is involved in numerous aspects of cellular and physiological function, including the regulation of the sleep-wake cycle, immune function, and antioxidant defense systems. Melatonin helps to initiate and maintain sleep by signaling the body's readiness for sleep. It also helps to regulate circadian rhythms, which are the natural 24-hour cycles that control various bodily functions. Melatonin has been shown to support antioxidant defenses by scavenging free radicals and enhancing the activity of antioxidant enzymes. It also plays a role in immune function by modulating the activity of immune cells.‡\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340828868,"sku":null,"price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/4c1a03e2f6a50eb5dfb40a2081f114957b1828d965a5f47e0650066ef0d2f2f1_5.avif?v=1782128490"},{"product_id":"melatonin-0-5-mg-60ct","title":"Melatonin 0.5 Mg 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Promotes the body's natural sleep cycle\u003cbr\u003e* Helps augment the natural functioning of the pineal gland\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003cbr\u003e* Contains 99.5% pure melatonin\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eMelatonin 0.5 mg and 3 mg capsules:\u003cbr\u003eAs a dietary supplement, take 1 capsule daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003cbr\u003eMelatonin liquid:\u003cbr\u003eAs a dietary supplement, take 1 dropper daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Natural sleep\/wake cycle support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland, which regulates the body's sleep\/wake cycle. Melatonin's primary role is regulation of the body's circadian rhythm, endocrine secretions and sleep patterns. Studies indicate that it facilitates the onset of sleep, as well as sleep efficiency.1\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Ferracioli-Oda E, et al. *PLoS One.*2013 May 17;8(5).\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* This supplement contains 99.5% synthetic melatonin\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340861636,"sku":null,"price":12.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/3283be749a7fd59f63ecfff6115e789641d7c60766b9189540e568526fcc50f8.avif?v=1782128542"},{"product_id":"melatonin-0-5-mg-180ct","title":"Melatonin 0.5 Mg 180ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Promotes the body's natural sleep cycle\u003cbr\u003e* Helps augment the natural functioning of the pineal gland\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003cbr\u003e* Contains 99.5% pure melatonin\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eMelatonin 0.5 mg and 3 mg capsules:\u003cbr\u003eAs a dietary supplement, take 1 capsule daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003cbr\u003eMelatonin liquid:\u003cbr\u003eAs a dietary supplement, take 1 dropper daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Natural sleep\/wake cycle support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland, which regulates the body's sleep\/wake cycle. Melatonin's primary role is regulation of the body's circadian rhythm, endocrine secretions and sleep patterns. Studies indicate that it facilitates the onset of sleep, as well as sleep efficiency.1\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Ferracioli-Oda E, et al. *PLoS One.*2013 May 17;8(5).\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* This supplement contains 99.5% synthetic melatonin\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340894404,"sku":null,"price":31.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/3283be749a7fd59f63ecfff6115e789641d7c60766b9189540e568526fcc50f8_1.avif?v=1782128609"},{"product_id":"melatonin-liquid-30ml","title":"Melatonin Liquid 30ml","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003ePromotes regulation of the body's circadian rhythm, endocrine secretions and sleep patterns\u003cbr\u003eHelps facilitate the onset of sleep, as well as sleep efficiency\u003cbr\u003eContains 99.5% pure melatonin\u003cbr\u003eMade with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eMelatonin 0.5 mg and 3 mg capsules:\u003c\/p\u003e\n\u003cp\u003eAs a dietary supplement, take 1 capsule daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003c\/p\u003e\n\u003cp\u003eMelatonin liquid:\u003c\/p\u003e\n\u003cp\u003eAs a dietary supplement, take 1 dropper daily, 1\/2 to 1 hour before bedtime, or as directed by your health professional.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eAges 18 and up\u003cbr\u003eNatural sleep\/wake cycle support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin is a hormone produced by the pineal gland, which regulates the body's sleep\/wake cycle. Melatonin's primary role is regulation of the body's circadian rhythm, endocrine secretions and sleep patterns. Studies indicate that it facilitates the onset of sleep, as well as sleep efficiency.1\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Ferracioli-Oda E, et al. *PLoS One.*2013 May 17;8(5).\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003eThis supplement contains 99.5% synthetic melatonin\u003cbr\u003eHypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275340927172,"sku":null,"price":37.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/8503ea159a791deaa83207baf086432dbc9097f6fd933212511dd9b036c019a4.avif?v=1782128665"},{"product_id":"melatonin-sr-60ct","title":"Melatonin-SR 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Promotes healthy sleep\u003cbr\u003e* Offers MicroActive® melatonin for sustained 6-hour support\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 1 capsule 30-60 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Sleep support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eMelatonin-SR provides sustained-release MicroActive® melatonin to promote healthy sleep. Melatonin is a hormone produced by the pineal gland, which regulates the body's sleep\/wake cycle.1 Melatonin's primary role is regulation of the body's circadian rhythm, endocrine secretions and sleep patterns. Studies indicate that it facilitates the onset of sleep, as well as sleep efficiency.2 MicroActive® is an innovative, patented delivery system that offers both improved absorption and sustained release. A pharmacokinetic study of MicroActive® melatonin demonstrated rapid uptake and prolonged presence in plasma up to six hours after a single dose.\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Vriend J, Reiter RJ. *J Pineal Res.* 2015 Jan;58(1):1-11.\u003cbr\u003e2. Zhdanova IV, et al.*J Clin Endocrinol Metab.*2001 Oct;86(10):4727-30.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eConsult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids. may be contraindicated for individuals taking corticosteroids.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Melatonin is synthetic\u003cbr\u003e* Carnauba wax is derived from leaves of the palm *Copernicia prunifera*\u003cbr\u003e* Hydroxypropyl methyl cellulose and microcrystalline cellulose derived from wood pulp\u003cbr\u003e* Sodium alginate is derived from brown seaweed\u003cbr\u003e* Hypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275341123780,"sku":null,"price":19.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/d0cc2980fadb8491ae219dd8d26056a235cb8181f7851b6ee83241d5dbfceb84.avif?v=1782129112"}],"url":"https:\/\/valvistapharmacy.com\/collections\/sleep-support.oembed","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}