{"product_id":"benfomax-90ct","title":"BenfoMax 90ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003eMaintains healthy advanced glycation end (AGE) product activity\u003cbr\u003ePromotes healthy glucose metabolism\u003cbr\u003eSupports optimal thiamine pyrophosphate activity\u003cbr\u003ePromotes vascular, retinal, kidney and neuronal health\u003cbr\u003eContains pure Japanese-manufactured benfotiamine\u003cbr\u003eMade with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 1 capsule, 1-3 times daily, with meals.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eAges 18 and up\u003cbr\u003eHealthy glucose metabolism support\u003cbr\u003eVascular, retinal, kidney and neuronal health\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eBenfotiamine, S-benzoylthiamine-Omonophosphate, is a fat-soluble vitamin B1 (thiamine) derivative that maintains healthy advanced glycation end (AGE) product activity to support vascular, nerve, retinal and kidney cellular health. Benfotiamine supports the function of several enzymes, including thiamine pyrophosphate and transketolase, which are involved in glucose metabolism and vascular function.1, 2 In a randomized crossover trial, benfotiamine supported healthy flow-mediated dilation and endothelial function in response to a heat-treated meal containing high levels of glycated proteins.3 In another randomized controlled study, benfotiamine supported healthy nerve conduction velocity and nerve comfort.4 Research suggests that benfotiamine may also maintain healthy renal glomeruli and retinal function, protein kinase C enzyme activity, and protein glycation.5 It may also maintain cytokine balance through modulation of NF-κB, which regulates the expression of immune mediators.6\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Frank T, et al. *Eur J Clin Pharmacol*. 2000 Jun;56(3):251-7\u003cbr\u003e2. Berrone E, et al. *. J Biol Chem* 2006 Apr 7;281(14):9307-13.\u003cbr\u003e3. Stirban A, et al. *Diabetes Care*.. 2006 Sep;29(9):2064-71.\u003cbr\u003e4. Winkler G, et al. *Arzneimittelforschung.* 1999 Mar;49(3):220-4.\u003cbr\u003e5. Haupt E, et al.*. Int J Clin Pharmacol Ther* 2005 Feb;43(2):71-7.\u003cbr\u003e6. Shoeb M, et al. *Free Radic Biol Med.* 2012 Jan 1; 52(1): 182, 190.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003ePure Encapsulations's BenfoMax contains pure Japanese-manufactured benfotiamine. Benfotiamine is synthetic\u003cbr\u003eAscorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003cbr\u003eHypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275316580548,"sku":null,"price":59.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/c6960da91aaa042263241cbac8744d675a395621731ac62c783e96413784609b.avif?v=1781956150","url":"https:\/\/valvistapharmacy.com\/products\/benfomax-90ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}