{"product_id":"cal-with-ipriflavone-350ct","title":"CAL+ with Ipriflavone 350ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDesigned to strengthen the skeletal system\u003c\/li\u003e\n\u003cli\u003eEnhances calcium absorption and its incorporation into bones\u003c\/li\u003e\n\u003cli\u003eSupports collagen, elastin and the formation of mineralized bone matrix\u003c\/li\u003e\n\u003cli\u003eMaintains healthy osteoclast activity\u003c\/li\u003e\n\u003cli\u003eBroad-spectrum combination of minerals and vitamins\u003c\/li\u003e\n\u003cli\u003eContains 400mg of calcium\u003c\/li\u003e\n\u003cli\u003eMade with high-quality vegetarian ingredients backed by verifiable science\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDirections \/ Usage:\u003c\/p\u003e\n\u003cp\u003eAs a dietary supplement, take 3 capsules, 1-2 times daily, with meals.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAges 18 and up\u003c\/li\u003e\n\u003cli\u003eHealthy skeletal system support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003c\/p\u003e\n\u003cp\u003eThis broad-spectrum combination of minerals, vitamins and herbs is formulated to aid in the formation and strengthening of the skeletal system. It provides a highly bioavailable form of calcium, a mineral essential not only for the maintenance of the functional integrity of the nervous, muscular and skeletal systems, but also cell membrane and capillary impermeability.1 This formula also provides substances that nutritionally support and enhance the absorption of calcium and the incorporation of calcium into bone. In addition, it provides nutrients essential to healthy bone structure and formation, the synthesis and strengthening of connective tissue in cartilage and bone, and the formation of elastin.2 Ipriflavone, an advanced addition to this formula, is a synthetic derivative of naturally occurring isoflavones. It supports healthy bone maintenance by promoting secretion of the hormone calcitonin and maintaining healthy osteoclast activity.3 Ipriflavone also supports type I collagen and the formation of mineralized bone matrix.4 Vitamin K enhances bone formation by carboxylating osteocalcin. This enables osteocalcin to bind to calcium and promote healthy bone mineralization.5 Furthermore, +CAL+® is enhanced with 10.7 mcg (428 IU) of vitamin D3 for bone health.6\u003c\/p\u003e\n\u003cp\u003eReferences:\u003c\/p\u003e\n\u003cp\u003e1. ADawson-Hughes B, et al.*N Engl J Med*. 1990 Sep 27;323(13):878-83.\u003c\/p\u003e\n\u003cp\u003e2. Strause L, et al.*J Nutr.* 1994 Jul;124(7):1060-4.\u003c\/p\u003e\n\u003cp\u003e3. Zhang X, Li SW, Wu JF, Dong CL, Zheng CX, Zhang YP, Du J. *Gynecol Endocrinol*.2010 Feb;26(2):76-80.\u003c\/p\u003e\n\u003cp\u003e4. Agnusdei D, et al. *Drugs Exp Clin Res*. 1989;15(2):97-104.\u003c\/p\u003e\n\u003cp\u003e5. Braam LA, et al. *Thromb Haemost*.\u003c\/p\u003e\n\u003cp\u003e6. Rahme M, et al.*J Bone Miner Res*. 2017 Jul;32(7):1486-1495.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003c\/p\u003e\n\u003cp\u003eNot to be taken by pregnant or lactating women. Vitamin K may be contraindicated with Coumadin (Warfarin). If you have any health condition or are taking any medication, particularly blood-thinning medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003c\/p\u003e\n\u003cp\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCalcium, magnesium, manganese, zinc, copper and boron are derived from earthen ore\u003c\/li\u003e\n\u003cli\u003eCitrate\/malate, glycinate and aspartate are synthetic\u003c\/li\u003e\n\u003cli\u003eVitamin D3 is derived from lanolin.\u003c\/li\u003e\n\u003cli\u003eIpriflavone and vitamin K1 are synthetically derived\u003c\/li\u003e\n\u003cli\u003eAscorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46306401517764,"sku":null,"price":90.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/43-cal-43-with-ipriflavone-210-s-cp2_1.avif?v=1782561673","url":"https:\/\/valvistapharmacy.com\/products\/cal-with-ipriflavone-350ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}