{"product_id":"e-p-o-evening-primrose-oil-250ct","title":"E.P.O. (evening primrose oil) 250ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Supports the look and feel of healthy skin\u003cbr\u003e* Promotes healthy prostaglandin E1 production and cytokine activity which may help support joint comfort\u003cbr\u003e* GLA provides cardiovascular function support in women when combined with EPA\/DHA\u003cbr\u003e* May provide premenstrual comfort\u003cbr\u003e* Source of the essential fatty acids including GLA\u003cbr\u003e* Produced using cold-pressed process without solvents\u003cbr\u003e* Convenient softgel capsule for easy dispensing\u003cbr\u003e* Made with high-quality ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 1 capsule, 1-4 times daily, with or between meals.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Healthy skin support\u003cbr\u003e* Cardiovascular and joint comfort\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eEvening primrose oil (E.P.O.) is cold-pressed and produced without the use of any solvents. Used for centuries as nutritional support for a wide range of physiological functions, several studies have indicated that E.P.O. may help support the look and feel of healthy skin.1 A clinical trial reported that E.P.O. supported healthy skin through a modulation of IFN-gamma.2 Another study revealed that E.P.O. promoted skin health and led to a more favorable shift in eicosanoid metabolism.3 Other studies suggest that E.P.O. may support healthy lipid metabolism and may provide oxidative protection by promoting glutathione reductase and transferase activities.4 A clinical trial reported that GLA in combination with EPA\/DHA significantly promoted healthy cardiovascular function in women.5 Additionally, E.P.O. may potentially be supportive of premenstrual comfort.6\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Muggli R. *Int J Cosmet Sci.* 2005 Aug;27(4):243-9.\u003cbr\u003e2. Yoon S, et al. *Skin Pharmacol Appl Skin Physiol.*2002 Jan-Feb;15(1):20-5.\u003cbr\u003e3. Yoshimoto-Furuie K, et al. *Nephron.* 1999 Feb;81(2):151-9.\u003cbr\u003e4. Lee SJ, et al. *Intern J Dairy Tech.* 2007. 60(1); 22-30.\u003cbr\u003e5. Laidlaw M, et al. *Am J Clin Nut.* 2003. 77(1); 37-42.\u003cbr\u003e6. Pruthi S, et al. *Altern Med Rev*. 2010 Apr;15(1):59-67.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003eEvening primrose oil is a cold-pressed oil produced without the use of any solvents\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275324182724,"sku":null,"price":72.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/7e7d62493af25930254ba2a09b6e20b2032fc200a8b1b1e60bac8a12f7eb4868_2.avif?v=1781967763","url":"https:\/\/valvistapharmacy.com\/products\/e-p-o-evening-primrose-oil-250ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}