{"product_id":"lipid-support-complex-60ct","title":"Lipid Support Complex 60ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Supports hepatic fat metabolism\u003cbr\u003e* Reduces oxidative stress\u003cbr\u003e* Supports vascular health\u003cbr\u003e* Promotes healthy uric acid levels\u003cbr\u003e* Clinically studied BergacynFF®\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 2 capsules daily with meals, or as directed by a health care professional.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Patients seeking support for healthy liver fat metabolism\u003cbr\u003e* Patients seeking support for healthy uric acid levels or oxidative stress\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eLipid Support Complex supports hepatic fat metabolism with a combination of berberine and clinically studied BergacynFF®, a patented extract blend of bergamot citrus and *Cynara cardunculus* . BergacynFF® supports lipid metabolism in the liver, with the added benefits of promoting healthy uric acid levels, decreasing oxidative stress and supporting vascular endothelial health.1-4 In a randomized, double blind, placebo-controlled clinical study involving 102 subjects, BergacynFF® (600 mg\/day) for 12 weeks resulted in significant support for liver fat metabolism, assessed by CAP scores.2 In a randomized, double blind, placebo-controlled clinical study involving 80 subjects, BergacynFF® (600 mg\/day) significantly improved serum markers of oxidative stress, with a reduction in circulating malondialdehyde (MDA) coupled with an increase in glutathione peroxidase (GPx) and superoxide disumutase (SOD) levels after 16 weeks. Supplementation also supported vascular endothelial function.^4^ This formula also provides berberine, an alkaloid that moderates lipid accumulation in liver cells in vitro.5-8 In preclinical models, berberine activates hepatic AMP kinase (AMPK) and sirutin 1 (SIRT1), which play important roles in supporting fat utilization in moderating fat synthesis in the liver.7, 8-10\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. **Ferro** Y, et al. *Medicina (Kaunas)*. 2022 Nov 26;58(12):1728.\u003cbr\u003e2. **Ferro** Y, et al. *Front Endocrinol (Lausanne)*. 2020 Aug 11;11:494.\u003cbr\u003e3. **Parafati** M, et al. *J Nutr Biochem*. (2015) 26:938-- 48.\u003cbr\u003e4. **Musolino** V, et al. *J Tradit Complement Med*. 2020 Feb 8;10(3):268-274.\u003cbr\u003e5. **Xu** X, et al. *FASEB J*. 2019 Jun;33(6):7289-7300.\u003cbr\u003e6. **Ionita-Radu** F, et al. *Int J Mol Sci*. 2024 Apr 10;25(8):4201.\u003cbr\u003e7. **Yu** M, et al. *Int J Biol Sci*. 2021 Apr 12;17(7):1693-1707.\u003cbr\u003e8. **Zhu** X, et al. *Free Radic Biol Med*. 2019 Sep;141:192-204.\u003cbr\u003e9. **Smith** BK, et al. *Am J Physiol Endocrinol Metab*. 2016 Oct 1;311(4):E730-E740.\u003cbr\u003e10. **Tian** C, et al. *Pharmacol Res*. 2024 May;203:107155.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eNot to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Bergamot orange extract is derived from *Citrus bergamia* fruit\u003cbr\u003e* Cardoon artichoke extract is derived from *Cynara cardunculus* leaf\u003cbr\u003e* Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003cbr\u003e* Hypo-allergenic plant fiber is derived from pine cellulose\u003cbr\u003e* Tri-magnesium citrate is derived from elemental ore and non-GMO glucose fermentation from non-GMO maize, molasses, and sugar beet or sugar cane\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275299901636,"sku":null,"price":60.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/lsc6_rgb.avif?v=1781887474","url":"https:\/\/valvistapharmacy.com\/products\/lipid-support-complex-60ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}