{"product_id":"puregenomics-b-complex-120ct","title":"PureGenomics® B-Complex 120ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003e* Addresses the nutrient requirements of common genetic variations in the methylation pathway\u003cbr\u003e* Supports cellular health, DNA synthesis, hormone and neurotransmitter production, and energy metabolism\u003cbr\u003e* Promotes energy production and nutrient metabolism\u003cbr\u003e* Offers vitamin B12 in unique blend of adenosylcobalamin and hydroxycobalamin\u003cbr\u003e* Contains Metafolin® L-5-MTHF, the naturally occurring, universally metabolized form of folate\u003cbr\u003e* Part of the PureGenomics® product line\u003cbr\u003e* Made with high-quality vegan ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003e* Ages 18 and up\u003cbr\u003e* Support for common genetic variations\u003cbr\u003e* B vitamin and general wellness support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003ePureGenomics® B-Complex is designed to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of B vitamins in highly researched and activated forms. Methylation is a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, DNA synthesis, hormone and neurotransmitter production and energy metabolism.1 Optimal levels of B vitamins have been associated with cellular, cardiovascular, neurological and psychological health.2, 3, 4, 5 B vitamins are essential to basal mitochondrial function as metabolic coenzymes, playing a key role in energy production and nutrient metabolism.6 Folate is offered in this formula as Metafolin® 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, providing support for individuals with genetic variations in the MTHFR gene.7 Vitamin B12 is offered as a combination of hydroxycobalamin and adenosylcobalamin. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. Adenosylcobalamin is an activated form stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism and healthy synthesis of neuronal myelin.8 Benfotiamine is a lipid-soluble, enhanced-retention thiamin derivative.\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Glier MB, Green TJ, Devlin AM. *Mol Nutr Food* *Res* 2014 Jan;58(1):172-82.\u003cbr\u003e2. Antoniades C, et al. *Circulation*. 2006 Sep 12;114(11):1193-201.\u003cbr\u003e3. den Heijer M, et al. *Arterioscler Thromb Vasc* *Biol.*. 1998 Mar;18(3):356-61\u003cbr\u003e4. Jacobs AM, et al. *Rev Neurol Dis*. 2011;8(1-2):39-47.\u003cbr\u003e5. Almeida OP, et al. *Ann Neurol*. 2010 Oct;68(4):503-10.\u003cbr\u003e6. Huskisson E, Maggini S, Ruf M. *J Int Med Res.*2007 May-Jun;35(3):277-89.\u003cbr\u003e7. Prinz-Langenohl R, et al.*Br J Pharmacol.*. 2009 Dec; 158(8): 2014?2021.\u003cbr\u003e8. L?vblad K, et al. *Pediatr Radiol.* 1997 Feb;27(2):155-8.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eIf you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003e* Vitamin B1 (thiamin HCl and benfotiamine), niacinamide, niacin, vitamin B5 (calcium pantothenate), vitamin B6 (pyridoxal HCl), folic acid (Metafolin® L-5-MTHF), biotin and choline are synthetic\u003cbr\u003e* Vitamin B2 (riboflavin) and vitamin B12 (hydroxycobalamin and adenosylcobalamin) are derived from corn dextrose fermentation\u003cbr\u003e* Ascorbyl palmitate is produced from corn dextrose fermentation and palm oil\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275343417540,"sku":null,"price":47.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/9b55188f273b54e6a094f5b825f123c72d152ef922ec01eca020a0d58417bf0c.avif?v=1782137038","url":"https:\/\/valvistapharmacy.com\/products\/puregenomics-b-complex-120ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}