{"product_id":"vitamin-a-carotenoids-90ct","title":"Vitamin A + Carotenoids 90ct","description":"\u003cp\u003eBenefits \u0026amp; Features:\u003cbr\u003eProvides preformed vitamin A, which bypasses genetic variations that limit conversion of beta-carotene\u003cbr\u003eSupports optical lens health and macular pigment density\u003cbr\u003eProvides antioxidant defenses to protect retinal health\u003cbr\u003ePart of the PureGenomics® product line\u003cbr\u003eMade with high-quality ingredients backed by verifiable science\u003c\/p\u003e\n\u003cp\u003eDirections \/ Usage:\u003cbr\u003eAs a dietary supplement, take 1 capsule daily, with a meal.\u003c\/p\u003e\n\u003cp\u003eIndications:\u003cbr\u003eAges 18 and up\u003cbr\u003eEye health\u003cbr\u003eImmune function support\u003c\/p\u003e\n\u003cp\u003eScience \u0026amp; Research:\u003cbr\u003eThe ability to convert provitamin A carotenoids, like beta carotene, into active vitamin A varies from one person to the next, owing to genetic variations that can limit enzyme activity. Single nucleotide polymorphisms (SNPs) in the gene encoding the enzyme BCMO1 (β-Carotene 15, 15'-monooxygenase 1) can decrease the conversion efficacy of carotenoids into retinal, the immediate precursor of vitamin A, by up to 69%.1 These common variations can be bypassed with dietary retinol (vitamin A).2 Since variations in the BCMO1 gene have also been associated with macular pigment density, this formula includes a blend of lutein, zeaxanthin and astaxanthin to promote macular health.3 Lutein and zeaxanthin are the two carotenoids found in macular pigment; as such, they act to support the integrity and density of the pigment, as well as optical lens health.4 Astaxanthin offers support for antioxidant defenses to protect retinal health.5\u003c\/p\u003e\n\u003cp\u003eReferences:\u003cbr\u003e1. Lietz G, et al. *J Nutr.*2012 Jan;142(1):161S-5S.\u003cbr\u003e2. Leung WC, et al.*FASEB J.*2009 Apr;23(4):1041-53.\u003cbr\u003e3. Feigl B, et al.*PLoS One.* 2014 Feb 19;9(2):e89069.\u003cbr\u003e4. Age-Related Eye Disease Study 2 (AREDS2) Research Group, Chew EY, Clemons TE, et al. *JAMA Ophthalmol.* 2014 Feb;132(2):142-9.\u003cbr\u003e5. Piermarocchi S, et al. *Eur J Ophthalmol.* 2012 Mar-Apr;22(2):216-25.\u003c\/p\u003e\n\u003cp\u003eWarning:\u003cbr\u003eVitamin A at levels above 3, 000 mcg (10, 000 IU) can lead to adverse side effects, including birth defects. If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003eStorage:\u003cbr\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003eSource:\u003cbr\u003eVitamin A and zeaxanthin are synthetic\u003cbr\u003eLutein is derived from marigold flower extract\u003cbr\u003eAstaxanthin is derived from *Haematococcus pluvialis* algae extract\u003cbr\u003eRed beet powder is derived from *Beta vulgaris* root\u003cbr\u003eHypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":46275348857028,"sku":null,"price":32.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/7168\/8900\/files\/b2a0d89d48afcfde9552728f537a5c708a92c0b237e6509f823f1ad4474e9e70.avif?v=1782148827","url":"https:\/\/valvistapharmacy.com\/products\/vitamin-a-carotenoids-90ct","provider":"Val Vista Pharmacy","version":"1.0","type":"link"}