It has a long history of use for supporting healthy cyclooxygenase, prostaglandin and leukotriene metabolism.1 It also appears to maintain healthy cell cycle function and antioxidant defenses.2 Furthermore, it supports the body's natural detoxification system and helps maintain healthy hepatic function. These actions are associated with its beneficial effects, including support for liver, colon, brain, musculoskeletal and cellular health.3, 4, 5Curcumin C3 Complex® has been the subject of scientific investigations at a number of hospitalsand universities. Studies indicate that curcumin maintains cellular health in various tissues, including the brain, where it maintains healthy immune cell activity. The gut microbiota and gut-brain axis may also play a part in mediating curcumin's brain health benefits.6, 7, 8