Aller-Essentials contains a blend of nutrients and herbal extracts designed to maintain healthy seasonal immune function. EpiCor® *Saccharomyces cerevisiae fermentate* contains numerous immune-enhancing bioactive metabolites designed to support both innate and adaptive immune response.1 Research suggests that it enhances natural killer cell activation, B cell and T cell function, and salivary IgA levels.2 In a double-blind, placebo-controlled trial involving 96 subjects, EpiCor® supported nasal comfort during a 12-week period in the spring. Additionally, it supported salivary IgA levels, an important first-line defense produced by the mucosal tissue.3 In a randomized, double-blind trial involving 75 individuals, *Tinospora cordifolia* provided significant support for a healthy immune response by maintaining normal nasal function as well as healthy neutrophil and eosinophil activity.4 A randomized, double-blind, placebo-controlled trial involving apple polyphenols reveals support for maintaining a healthy nasal lining and nasal function.5 Quercetin, hesperidin and vitamin C provide additional support for stabilizing mast cells.6, 7, 8
