This vegetarian formula provides wide range herbal and nutritional support for the adrenal glands. Panax ginseng and *Eleutherococcus senticosus* , or eleuthero, are highly recognized adaptogens, promoting physiological balance and moderating occasional stress. In part, they help to moderate the production of adrenocorticotrophic hormone (ACTH) and ultimately corticosterone activity.1, 2 Corticosterone promotes the conversion of amino acids into carbohydrates and glycogen by the liver and stimulates glycogen formation in the tissues, supporting optimal energy reserves.3 *Rhodiola rosea* , containing rosavins and salidrosides, also acts to balance hypothalamic-pituitary-adrenal activity. Rhodiola can have a calming effect on the central nervous system and supports healthy adrenal gland function.4 In particular, rhodiola may moderate the effects of occasional physical and emotional stress.5 Recently, a double-blind, crossover study suggested that rhodiola may help to moderate mild fatigue under stressful conditions.6 Astragalus and ashwagandha promote immune function and complement the adaptogenic activity of this formula.7, 8 Pantothenate, also known as vitamin B5 , is essential for healthy adrenal function.9 Collectively, these ingredients support the health and activity of the adrenal glands.
